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Maleic acid is a water-soluble, organic dicarboxylic acid and the cis-isomer of butenedioic acid. It can be converted to fumaric acid via isomerization. Salts, esters, and anions of maleic acid can be used in biochemical reactions and pharmaceutical drugs.
Prasugrel hydrochloride (CAS 389574-19-0) is a small molecule inhibitor that targets platelet activation by antagonizing the P2Y12 adenosine diphosphate (ADP) receptor on platelet surfaces By inhibiting this receptor prasugrel impedes ADP-mediated platelet aggregation a critical process in thrombus formation In biochemical assays prasugrel hydrochloride demonstrates an IC50 of 1 8 M for platelet inhibition This compound is utilized in biomedical research to investigate platelet signaling pathways and to model antithrombotic interventions in vitro
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Maleic hydrazide (CAS: 123-33-1) is a systemic plant growth regulator and herbicide. It functions as an inhibitor of nucleic acid and protein synthesis, making it useful in agriculture despite its known mutagenic and clastogenic effects. This product is supplied as a 10 mM solution in 1 mL of DMSO, with a purity of 99.98%.
Acts as a systemic plant growth regulator and herbicide
Inhibits nucleic acid and protein synthesis
Exhibits lower IC50 values for cell lines compared to Ethephon
Shows least cytotoxicity on Vero cells, followed by Hep2 and HepG2 cells
Has low acute toxicity by oral, dermal, and inhalation routes of exposure
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Maleic hydrazide-d2 is a deuterium-labeled form of Maleic hydrazide, a systemic plant growth regulator and herbicide. It inhibits nucleic acid and protein synthesis and can be used as a tracer or internal standard for quantitative analysis in techniques such as NMR, GC-MS, or LC-MS.
Can be used as a tracer
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Deuteration may impact pharmacokinetic and metabolic profiles of drugs
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Prasugrel hydrochloride (CAS 389574-19-0) is a small molecule inhibitor that targets platelet activation by antagonizing the P2Y12 adenosine diphosphate (ADP) receptor on platelet surfaces By inhibiting this receptor prasugrel impedes ADP-mediated platelet aggregation a critical process in thrombus formation In biochemical assays prasugrel hydrochloride demonstrates an IC50 of 1 8 M for platelet inhibition This compound is utilized in biomedical research to investigate platelet signaling pathways and to model antithrombotic interventions in vitro
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Prasugrel hydrochloride (CAS 389574-19-0) is a small molecule inhibitor that targets platelet activation by antagonizing the P2Y12 adenosine diphosphate (ADP) receptor on platelet surfaces By inhibiting this receptor prasugrel impedes ADP-mediated platelet aggregation a critical process in thrombus formation In biochemical assays prasugrel hydrochloride demonstrates an IC50 of 1 8 M for platelet inhibition This compound is utilized in biomedical research to investigate platelet signaling pathways and to model antithrombotic interventions in vitro
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Prasugrel is a thienopyridine and proagent that inhibits platelet function. It is an orally active and potent P2Y12 receptor antagonist, inhibiting ADP-induced platelet aggregation.
Inhibits platelet function
Orally active
Potent P2Y12 receptor antagonist
Inhibits ADP-induced platelet aggregation
For research use only
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
PRX-08066 is a selective and orally active 5-hydroxytryptamine receptor 2B (5-HT2BR) antagonist with a Ki of 3.4 nM. It inhibits the MAPK pathway, 5-HT release, and the expression of fibrotic factors. This compound also inhibits the proliferation of KRJ-I cells and induces apoptosis through caspase-3 activation. Additionally, it has been shown to inhibit pulmonary vascular remodeling and is considered for use in pulmonary arterial hypertension (PAH) and neuroendocrine tumors (NET).
Selective and orally active 5-HT2BR antagonist
Inhibits MAPK pathway and 5-HT release
Inhibits expression of fibrotic factors (TGFβ1, CTGF, and FGF2)
Inhibits proliferation of KRJ-I cells
Induces apoptosis through caspase-3 activation
Inhibits pulmonary vascular remodeling
Potential for use in pulmonary arterial hypertension (PAH)
Potential for use in neuroendocrine tumors (NET)
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